EFFECTS OF ESSENTIAL OIL MOUTHWASH IN

CLINICAL 2 : Effects of Essential Oil Mouthwash in Oral Hygiene Regimens

OBJECTIVE:

To evaluate the efficacy of various oral hygiene regimens in the prevention and reduction of plaque and gingivitis.

STUDY DESIGN

Single center, randomized, supervised, examiner blind, controlled clinical trial conducted at ADA-Qualified site.

• Following a complete prophylaxis, subjects were examined for oral soft tissue status, plaque, gingivitis, and gingival bleeding at Baseline, 4 weeks, and 12 weeks.
• If assigned to a flossing group, subjects were given flossing instructions and demonstrated competency.
• Product use was supervised once daily virtually on weekdays with second daily and weekend product use unsupervised.

STUDY PARTICIPANTS

• 213 subjects (18-60 years of age due to COVID- related health restrictions) with mild-to-severe gingivitis and no severe periodontitis, with no entry criteria on MGI/plaque, but must have a minimum of 10% gingival bleeding sites.
• The efficacy outcomes included interproximal and whole-mouth mean modified TPI, mean MGI, gingival bleeding, bleeding on probing depth, and probing depth.

ADDITIONAL RESULTS

This study also demonstrated that adding Listerine® Antiseptic Cool Mint to twice-daily brushing provided statistically significant reductions in gingivitis, gingival bleeding and probing depth compared to brushing.

1. Mean Turesky Plaque Index (TPI)
**P < 0.025 superiority vs. Brushing only.
P<0.0125 superiority vs. Brush/Floss. Clinical 2 control = Brush only.

Reference: 1. Bosma, M. L., McGuire, J. A., Sunkara, A., Sullivan, P., Yoder, A., Milleman, J., & Milleman, K. (2022). Efficacy of Flossing and Mouthrinsing Regimens on Plaque and Gingivitis: A randomized clinical trial. American Dental Hygienists' Association, 96(3), 8-20.